US overdose deaths continue decline in 2025

    Provisional CDC data shows that U.S. overdose deaths fell through most of last year.

    • The details: The new data runs through August 2025 and represents the first update of monthly provisional overdose deaths since the government shutdown in October.

    The findings:

    • An estimated 73,000 people died from overdoses in the 12-month period ending August 2025, down 21% from the 92,000 in the previous 12-month period.
    • That includes an estimated 47,000 overdose deaths involving opioids (over 45,000 of which involved fentanyl), nearly 28,000 involving psychostimulants with abuse potential (methamphetamine), and nearly 20,000 involving cocaine.
    • Deaths were down in all states except Arizona, Hawaii, Kansas, New Mexico, and North Dakota.

    Why it’s important: Overdose deaths have been falling for more than two years, the longest drop in decades.

    But: The decline is slowing, and the monthly death toll is still not back to what it was before COVID.

    Read more: US overdose deaths fell through most of 2025, federal data reveals