More than 1.6 million Americans could die from drugs, alcohol and suicide over the next decade, a new report concludes.

USA Today reports the findings come from the Trust for America’s Health and the Well Being Trust. The nonprofit group found in 2015, there were 39.7 deaths per 100,000 U.S. residents due to drugs, alcohol and suicide, compared with 23.1 deaths per 100,000 in 1999—a 72 percent increase. That number could rise to 56 deaths per 100,000 by 2025, the group said.

“We see a connection among the three epidemics,” said John Auerbach, President and CEO of the Trust for America’s Health. “They are all behavioral health-related — that is, they have a substance abuse or mental health diagnosis associated with them.”