Risk of developing benign breast disease increases five-fold among women who drank alcohol six or seven days a week during their teens and early 20s, according to research from the National Cancer Institute.

Benign breast disease is a known risk factor for breast cancer, researchers noted. Symptoms include hard lumps in the breasts, irregular cysts, breast discomfort, sensitive nipples, and itching.

Reuters reported April 12 that researcher Catherine Berkey of Harvard Medical School and colleagues drew their conclusions from a study of about 6,900 women ages 16-23. About one percent of the women reported having benign breast disease in a followup study at ages 18-27.

“Our study results give older girls and adolescents another reason to avoid alcohol,” said Berkey.

The study appears in the journal Pediatrics.