Addiction and risky substance use constitute the largest preventable and most costly public health problem in the U.S., totaling over $467 billion a year. Yet of every state and federal tax dollar spent on substance use and addiction, less than two cents goes toward prevention and treatment, while 96 cents goes toward addressing the consequences of our failure to prevent and treat the disease.


In each of the reports, white papers, books, journal articles, editorials and blog posts that The National Center on Addiction and Substance Abuse has published or disseminated over the years, a central theme has been to employ the most valid and reliable research findings available to identify practical and effective policies and practices. In this guide, we have compiled a comprehensive set of effective policies and practices that delineates specific actions for improving the prevention and treatment of risky substance use and addiction in the U.S. The guide also addresses important and emerging issues, including those related to:

Recommendations and conclusions

Effectively addressing addiction and risky substance use requires improvements in:

To accomplish these goals, policies and practices should be based on solid research evidence.