About the Medicine Abuse Project

Overdose deaths have reached record highs, and more than 75% are linked to opioids. In 2021, there were over 106,000 overdose deaths, equivalent to 292 per day. Of the 8.9 million people who misused opioids in 2022, the vast majority misused prescription pain relievers. Additionally, increasing numbers of these deaths, particularly among youth, are due to counterfeit illicit pills that individuals believe to be oxycontin, Xanax, benzodiazepines or other substances, but that contain lethal doses of fentanyl. As a result, reducing young people’s initiation of any type of medicine misuse is more critical and urgent than ever.

The Partnership to End Addiction (formerly the Partnership for Drug-Free Kids) has been addressing the opioid epidemic since the early 2000s, and in 2012 brought together a group of partners from the public and private sectors to form the Medicine Abuse Project. This national action campaign aims to reduce teen initiation of medicine misuse. It provides comprehensive resources for parents and caregivers, law enforcement officials, health care providers, educators and others so that everyone can take a stand and help end this epidemic.

To support health care providers, the Partnership created an education campaign specifically for opioid prescribers. Search and Rescue provides medical professionals with the tools and resources they need to help patients avoid prescription drug misuse and addiction.

Funding Partners

On behalf of the families we serve, thank you to all of the partners who make our work possible.

Interested in becoming a part of the Medicine Abuse Project? Learn more about partnership opportunities.

Gold $250K

Jazz Pharmaceuticals logo

Google logo

Silver $100K

CVS health logo 200x50

Daiichi-Sankyo logo

abbvie logo

Bronze $50K

Pfizer logo

Champion $25K

CHPA Logo 200x102

Government partners

Bureau of Justice Alliance

Centers for Disease Control and Prevention (CDC)

U.S. Department of Justice Drug Enforcement Administration (DEA)

Food and Drug Administration

National Institute on Drug Abuse (NIH)

Office of National Drug Control Policy (ONDCP)

Substance Abuse and Mental Health Services Administration (SAMHSA)

U.S. Department of Justice Office of U.S. Attorneys

National partners

Alliance for Safe Online Pharmacies (ASOP)

American Academy of Family Physicians

American Academy of Pediatrics

American Association for the Treatment of Opioid Dependence

American Association of Oral and Maxillofacial Surgeons

American Association of Poison Control Centers

American College of Emergency Physicians

American College of Preventative Medicine

American Dental Association (ADA)

The American Medicine Chest Challenge

American Society of Anesthesiologists

Association of State Criminal Investigative Agencies

Caron Treatment Centers

Center for Safe Internet Pharmacies

Healthcare Distribution Alliance

International Association of Campus Law Enforcement Administrators

National Association of Attorneys General

Aware Rx Prescription Drug Safety Program

National Association of Drug Court Professionals

National Association of Drug Diversion Investigators

National Association of Student Nurses

National Association of State Alcohol and Drug Abuse Directors

National Association of State Controlled Substances Authorities

National Council on Patient Information and Education

National Narcotics Officers’ Associations’ Coalition

National Education Association Health Information Network

Safe Homes Coalition

The Herren Project

The Mario Do Right Foundation

The National Center on Addiction and Substance Abuse Family Day

Treatment Research Institute

State and local partners

ACT Missouri

Alianza Para Un Puerto Rico Sin Drogas

Any Lab Test Now!

Behind the Orange Curtain

Center for Addiction Recovery and Education

California Friday Night Live Partnership

Colorado Meth Project

Denver Resource for Awareness and Prevention

Drug Overdose Prevention Education

Drug-Free Arizona

Fighting Addiction Through Education (FATE)

The Governor’s Prevention Partnership

HC Drug Free

Hope2Gether Foundation

Office of Drug Control Policy

Massachusetts Medical Society

Montana Meth Project

Mothers Against Prescription Drug Abuse

Mount Airy, NC Police Department

P.E.A.C.E. Foundation

Palm Beach County Substance Awareness Coalition

Partnership at Drug-Free Iowa.org

Drug-Free NC

Partnership for a Drug-Free New Jersey

Ohio Department of Alcohol and Drug Addiction Services

Pine State Marketing

Power of Pain Foundation

Prevent! The Substance Abuse Prevention Coalition of Clark County

Prevention First


Substance Abuse Free Environment (SAFE)

Save a Star Drug Awareness Foundation

Schuylkill Prevention Partnership

Staten Island Partnership for Community Wellness

The Committee for Hispanic Children and Families

The Council on Alcohol and Drug Abuse

The Generation Rx Initiative

The Skeeterhawk Experiment

Wyoming Meth Project