Narcan, a brand of naloxone nasal spray, is now available over-the-counter and can be found at major pharmacy chains such as Walgreen’s, CVS, Rite Aid, Target and Wal-Mart, as well as some independent drugstores. Other brands of nasal sprays and injectable naloxone are often available from public health agencies or community organizations. Naloxoneforall.org provides state-based information on accessing naloxone along with related resources and services.
No, it only works to reverse an overdose involving opioids.
Yes, naloxone is a very safe drug and will not adversely impact someone who has overdosed on other drugs or alcohol.
No, if someone is in respiratory distress the best course of action is to call 911 and administer naloxone along with rescue breathing.
Naloxone only last for 30 to 90 minutes so it’s possible that the person could go into respiratory arrest again due to the opioids still in their system. Medical professionals can help provide the necessary treatment to prevent respiratory failure. In 2023, the FDA approved a nalmefene nasal spray (brand name Opvee) which is meant to last longer than naloxone and decrease the risk of re-overdose but it may also cause longer-lasting withdrawal symptoms.
Yes, overdoses involving fentanyl may require repeated administrations of naloxone to restore breathing.
The relapse rate associated with opioid use has been estimated to be as high as 90 percent. As a precautionary measure, it’s important to have naloxone in the home. Just as you don’t anticipate having a fire, you probably have a smoke detector in the home – this is the same kind of precautionary measure that you hope you never have to use.
Many states have passed overdose prevention laws, which support treatment instead of arrests. Check your state’s laws.
Most states have passed Good Samaritan Laws for the protection of the person administering the naloxone. Check your state’s laws.
Call 911 and perform rescue breathing until the paramedics arrive.
Price and availability vary. Over-the-counter Narcan is currently retailing for approximately $45 for two doses. Some formulations are covered by insurance policies. Free naloxone may also be available in your community. Naloxoneforall.org provides state-based information on accessing naloxone along with related resources and services.
You can also find current prices and providers in your area by visiting goodrx.com. Add your zip code and type in “Narcan.”
Some manufacturers will provide naloxone at no charge for people who cannot afford the cost. Contact the manufacturer’s website – such as Narcan – for information on these programs.
There is an expiration date on naloxone, however research indicates that it can be effective well beyond the expiration date on packaging; in some cases months and years later. The safest practice is to get a replacement (setting a reminder on your phone’s calendar) but in the case of an emergency, it’s better to use an expired dose than to not administer anything.
Yes, check the packaging to see what temperature range is recommended. Generally, room temperature is advised.
No, there is no evidence that shows drug usage increases as a result of having naloxone available. Most overdoses among young people occur at home with a bystander present so it’s always best to err on the safe side and be prepared in case of an emergency.